https://www.lapislight.com/lapislight/blog daily 0.75 2026-03-29 https://www.lapislight.com/lapislight/blog/protein-amounts-cgek-p78wbj-cd8qq-p4bsl-ahon-rj7smix monthly 0.5 2025-12-05 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/5ecf5638-a025-442e-a7fc-93c801c28a82/EBioMedicine.png Functional Medicine Blog - “How much protein should I eat?” - The impact of dietary protein intake on longevity and metabolic health https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/0666067e-0c41-4ef1-ace3-31cfc4efe1d9/Methionine+Restriction.png Functional Medicine Blog - “How much protein should I eat?” - Make it stand out MetR [methionine restriction] may be a candidate dietary intervention for longevity and metabolic health through its effects that are exerted via multiple mechanisms. A Mediterranean diet or the DASH diet may be useful for reducing the consumption of animal protein, particularly red meat, to achieve MetR. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/78a8ae17-bcfe-44be-8167-4ac2eee8b19b/Protein+amounts+per+body+weight+by+age.png Functional Medicine Blog - “How much protein should I eat?” - Make it stand out These are rounded, evidence‑aligned ranges, not rigid prescriptions; clinical conditions (kidney disease, liver disease, etc.) can alter safe upper limits. Because kidney and other comorbidities are common in older adults, these ranges should be individualized with a clinician or dietitian, especially when approaching or exceeding ~0.8–0.9 g/lb (~1.8–2.0 g/kg) per day.pmc.ncbi.nlm.nih+3 https://www.lapislight.com/lapislight/blog/menopause-remedy-qs-ittsvh-a5dhu-wp955n-wd8m5 monthly 0.5 2025-12-03 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/def96f3f-4426-4689-84e1-e3854151a87c/Menopause.png Functional Medicine Blog - An overlooked remedy during menopause Research on a clinically important aspect of menopause self-care that is rarely addressed in health care. https://www.lapislight.com/lapislight/blog/heart-attackwomen-fiwxv-w09vba-lp3dh-y9cbl-wvkg-sx8b2-avtol-6cvf9-49mne monthly 0.5 2025-12-01 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/30f0b5ae-3eae-430a-bc0e-35f4aa99e37b/Causes+of+Myocardial+Infarction+in+Younger+Patients.png Functional Medicine Blog - More than half of younger women’s heart attacks are from nontraditional causes - Causes other than atherosclerosis caused 53% of the heart attacks in women less than 65 years old in this large population. https://www.lapislight.com/lapislight/blog/breast-cancer-diabetes-mxdpo-w54nvy-lp3dh-q3bhu-jocb-es7n3-avtol-3bng5-eobnz monthly 0.5 2025-10-05 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/c982a1dd-17a2-44ec-8946-cf5bed736176/Increased+aggression+of+PDOs+of+breast+cancer.png Functional Medicine Blog - Breast cancer is made more aggressive by type 2 diabetes exosomes - Exosomes in diabetes can reprogram immune cells in tumors, allowing the cancer to grow and spread. https://www.lapislight.com/lapislight/blog/primary-aldosteronism-hypertension-bmwsp-b73nvb-qf6cs-e9bma-soib-vb3e2-zpdrn-5jde3 monthly 0.5 2025-09-02 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/3144b726-f31b-4ea7-a6b0-e12a529c56e8/Journal+of+Clinical+Endocrinology+%26+Metabolism.png Functional Medicine Blog - All with high blood pressure should be screened for primary aldosteronism - The new clinical practice guideline from the Endocrine Society urges all providers to screen anyone with hypertension for primary aldosteronism. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/c4120200-e994-41e5-a10e-9beb61e9b01f/New+England+Journal+of+Medicine.png Functional Medicine Blog - All with high blood pressure should be screened for primary aldosteronism “Among patients with uncontrolled or resistant hypertension, the addition of baxdrostat, an aldosterone synthase inhibitor, to background therapy resulted in a significantly lower seated systolic blood pressure at 12 weeks than placebo.” https://www.lapislight.com/lapislight/blog/autoimmune-inflammation-psychiatric-hvbru-w09cvb-ac3nj-l2cvw-pzqg-vg9w3-cpsxm monthly 0.5 2025-08-31 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/23b3ec9b-d2c7-487e-b77c-0bf13c679fd4/BMJ+Mental+Health.png Functional Medicine Blog - Autoimmune inflammation significantly increases risk of mood disorders - New research shows that the chronic inflammation of autoimmunity is associated with nearly a two-fold increased risk for psychiatric disorders including depression, bipolar disorder, and anxiety. https://www.lapislight.com/lapislight/blog/vitamin-b12-jbnck-l38cxp-gu8m-v3maw-dexs-cde8i8-xswpb monthly 0.5 2025-03-16 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1548c1f0-43b3-4305-ad4a-a9a219de8335/Annals+of+Neurology.png Functional Medicine Blog - Serum levels of Vitamin B12 are not an accurate indicator of B12 functional status - Blood tests for vitamin B12 can be very misleading https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/7b842986-8d3e-45be-8849-8221d5cc6887/Vitamin+B12+transport+proteins.png Functional Medicine Blog - Serum levels of Vitamin B12 are not an accurate indicator of B12 functional status - Make it stand out “At low levels of B12, specifically when bound to transcobalamin for cellular uptake, evidence of slower conductivity in the brain could point toward impaired myelin. At high levels of B12, specifically when bound to the biologically inert transport protein haptocorrin, biomarkers of neurodegeneration appear in the serum, indicating neuroaxonal injury.” https://www.lapislight.com/lapislight/blog/breast-cancer-insulin-bhwod-x67mbu-qm9u-a4bny-taxs-bw8n5 monthly 0.5 2025-03-11 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/dad1feeb-64f9-419f-ad82-11ba796ba45f/Molecular+Cancer+Research.png Functional Medicine Blog - Insulin resistance increases breast cancer aggressiveness - Insulin resistance makes breast cancer more aggressive and promotes brain metastasis. https://www.lapislight.com/lapislight/blog/hypertension-bloodpressure-supine-vnwlc-b98xcd-ma6q-d9leb-xgdkh monthly 0.5 2025-03-08 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/70f7472c-af81-4217-8a18-c38619971567/JAMA+Cardiology.png Functional Medicine Blog - Blood pressure taken lying down is a better predictor of cardiovascular disease - Supine Blood Pressure and Risk of Cardiovascular Disease and Mortality https://www.lapislight.com/lapislight/blog/triglyceride-glucose-index-cihw-m4slt-prn5c monthly 0.5 2026-03-29 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/da8dd821-522f-4ead-8554-ff040d5bad6a/International+Journal+of+Cardiology.png Functional Medicine Blog - The Triglyceride–Glucose Index is a powerful biomarker for cardiovascular disease, depression, dementia, cancer and much more The Triglyceride–Glucose Index is proving to be a more accurate predictor of cardiovascular disease. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/0ee1ef77-d05c-4556-bade-471d4c51aff2/Circulation.png Functional Medicine Blog - The Triglyceride–Glucose Index is a powerful biomarker for cardiovascular disease, depression, dementia, cancer and much more A cluster of papers published in the journal Circulation serve as a summary introduction to the CKM model for those still unfamiliar. “Poor cardiovascular-kidney-metabolic (CKM) health is a major determinant of premature morbidity and mortality. Consequently, developing comprehensive strategies to augment CKM health across the life course is a key clinical and public health priority.” https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/25c94a06-660a-45c6-9067-aa0738cd88d9/Scientific+Reports.png Functional Medicine Blog - The Triglyceride–Glucose Index is a powerful biomarker for cardiovascular disease, depression, dementia, cancer and much more - Elevated triglyceride glucose index is associated with advanced cardiovascular kidney metabolic syndrome https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1c4f029d-a626-4000-b8fa-50eaf5e69b31/Renal+Failure.png Functional Medicine Blog - The Triglyceride–Glucose Index is a powerful biomarker for cardiovascular disease, depression, dementia, cancer and much more - The impact of the triglyceride-glucose index on the deterioration of kidney function in patients with cardiovascular-kidney-metabolic syndrome https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/8c94dc52-c134-46ba-8a29-0998672acad8/Journal+of+the+American+Heart+Association.png Functional Medicine Blog - The Triglyceride–Glucose Index is a powerful biomarker for cardiovascular disease, depression, dementia, cancer and much more - The Triglyceride–Glucose Index is associated with unstable plaque, the dangerous soft and gooey form that produces the clots that cause heart attacks and strokes. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/c6e81b75-38cf-4d6a-9ca8-840e8ff927ff/Nutrition%2C+Metabolism+and+Cardiovascular+Diseases.png Functional Medicine Blog - The Triglyceride–Glucose Index is a powerful biomarker for cardiovascular disease, depression, dementia, cancer and much more - The TyG Index is superior to HOMA-IR as a metric for insulin sensitivity. Given that insulin resistance is at the core of the damage associated with the cardio-kidney-metabolic syndrome, this is particularly important. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/372a4a01-2f92-4afc-a30b-753be1b1d1e0/Preventive+Medicine+Reports.png Functional Medicine Blog - The Triglyceride–Glucose Index is a powerful biomarker for cardiovascular disease, depression, dementia, cancer and much more - Triglyceride glucose index: A new biomarker in predicting cardiovascular risk https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/2a8039bf-808e-44b7-9776-3951046f56c0/The+Lancet+Europe.png Functional Medicine Blog - The Triglyceride–Glucose Index is a powerful biomarker for cardiovascular disease, depression, dementia, cancer and much more - Impact of surrogates for insulin resistance on mortality and life expectancy in primary care: a nationwide cross-sectional study with registry linkage And in research published in the prestigious journal The Lancet, the authors note: “Insulin resistance (IR) is an important risk factor for multiple chronic diseases, increasing mortality and reducing life expectancy.” https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/722bcaf7-6538-489e-84a5-57cff5c0be4d/Cardiovascular+Diabetology.png Functional Medicine Blog - The Triglyceride–Glucose Index is a powerful biomarker for cardiovascular disease, depression, dementia, cancer and much more TyG Index and carotid imtima-media thickness (c-IMT) https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/ae8185ad-03cf-4576-9aa0-aac88a3fa31f/European+Journal+of+Preventive+Cardiology.png Functional Medicine Blog - The Triglyceride–Glucose Index is a powerful biomarker for cardiovascular disease, depression, dementia, cancer and much more And arterial stiffness is one of the mediators for insulin-related atherosclerotic cardiovascular pathology as demonstrated in this paper. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/7aeaa0c9-3a9c-4d67-8e5a-0d445b003e4f/International+Journal+of+General+Medicine.png Functional Medicine Blog - The Triglyceride–Glucose Index is a powerful biomarker for cardiovascular disease, depression, dementia, cancer and much more Naturally, with the arterial stiffness and other endovascular effects there is a strong association with hypertension as shown in this paper. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/21b60ce8-f431-49ba-a3f6-4c87bde48d73/Lipids+in+Health+and+Disease.png Functional Medicine Blog - The Triglyceride–Glucose Index is a powerful biomarker for cardiovascular disease, depression, dementia, cancer and much more - Triglyceride glucose index is a useful marker for predicting subclinical coronary artery disease in the absence of traditional risk factors https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/25c94a06-660a-45c6-9067-aa0738cd88d9/Scientific+Reports.png Functional Medicine Blog - The Triglyceride–Glucose Index is a powerful biomarker for cardiovascular disease, depression, dementia, cancer and much more And in Clinical predictive model of new-onset atrial fibrillation in patients with acute myocardial infarction after percutaneous coronary intervention in Scientific Reports, the TyG Index is an indicator of new-onset afib (NOAF) after recovery from a heart attack. A paper published in the same journal found the TyG Index was effective at detecting higher risk for all-cause mortality after PCI treatment for a heart attack. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/8a031e2e-350c-4a7e-b2ec-95900578b3be/Frontiers+in+Endocrinology.png Functional Medicine Blog - The Triglyceride–Glucose Index is a powerful biomarker for cardiovascular disease, depression, dementia, cancer and much more The association between triglyceride-glucose index and neutrophil-lymphocyte ratio and all-cause mortality in the general US population: NHANES 2001–2018 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/525d1452-4a82-4189-8ba0-9cb22958ea60/International+Urogynecology+Journal.png Functional Medicine Blog - The Triglyceride–Glucose Index is a powerful biomarker for cardiovascular disease, depression, dementia, cancer and much more - Cardiometabolic Index and Stress Urinary Incontinence in US Women: The Mediating Role of the Triglyceride Glucose Index Stress urinary incontinence (SUI) is a prevalent condition among women, significantly impairing their quality of life. Emerging evidence suggests that metabolic dysfunction may play a role in the development of SUI. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/2356755f-b622-4545-ac23-76e7f37c814c/Journal+of+Affective+Disorders.png Functional Medicine Blog - The Triglyceride–Glucose Index is a powerful biomarker for cardiovascular disease, depression, dementia, cancer and much more Exploring the triglyceride-glucose index's role in depression and cognitive dysfunction: Evidence from NHANES with machine learning support https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/a34908bd-b0a6-4354-b8f1-c6d17019ba69/Neuroscience+%26+Biobehavioral+Reviews.png Functional Medicine Blog - The Triglyceride–Glucose Index is a powerful biomarker for cardiovascular disease, depression, dementia, cancer and much more The importance of assessing the triglyceride-glucose index (TyG) in patients with depression: A systematic review https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/77307724-6077-4028-a689-26337be712b9/Journal+of+Clinical+Medicine.png Functional Medicine Blog - The Triglyceride–Glucose Index is a powerful biomarker for cardiovascular disease, depression, dementia, cancer and much more - Role of Peripheral and Central Insulin Resistance in Neuropsychiatric Disorders https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/e0d87a85-ea0d-4028-8773-f82b220f0383/Insulin+Signaling.png Functional Medicine Blog - The Triglyceride–Glucose Index is a powerful biomarker for cardiovascular disease, depression, dementia, cancer and much more - Make it stand out Decreased apoptosis and autophagy = diminished ability to maintain and renew brain cells. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/700516a7-d0e4-4080-9fc4-5dd59563717b/Brain+and+Behavior.png Functional Medicine Blog - The Triglyceride–Glucose Index is a powerful biomarker for cardiovascular disease, depression, dementia, cancer and much more - Exploring the Association Between Cognitive Decline and Triglyceride-Glucose Index: A Systematic Review and Meta-Analysis https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/9c8a935e-d37a-4019-ad58-bc1249170f34/American+Journal+of+Preventive+Medicine.png Functional Medicine Blog - The Triglyceride–Glucose Index is a powerful biomarker for cardiovascular disease, depression, dementia, cancer and much more - Association of the Triglyceride-Glucose Index With Risk of Alzheimer's Disease: A Prospective Cohort Study https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/63e707a4-ff36-4cfd-a020-932fa062fb9b/Frontiers+in+Aging+Neuroscience.png Functional Medicine Blog - The Triglyceride–Glucose Index is a powerful biomarker for cardiovascular disease, depression, dementia, cancer and much more - Association between the triglyceride glucose index and cognitive impairment and dementia: a meta-analysis https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/302a6b57-4707-4bcf-81ab-1a9a932296d9/Frontiers+in+Endocrinology.png Functional Medicine Blog - The Triglyceride–Glucose Index is a powerful biomarker for cardiovascular disease, depression, dementia, cancer and much more - Relationship between triglyceride-glucose index and cognitive function among community-dwelling older adults: a population-based cohort study https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/012ae858-2163-407c-a21b-3faf8fc6fbc9/Hormone+and+Metabolic+Research.png Functional Medicine Blog - The Triglyceride–Glucose Index is a powerful biomarker for cardiovascular disease, depression, dementia, cancer and much more - Association Between Triglyceride Glucose Index with Cognitive Impairment and Dementia in Adult Population: A Meta-Analysis https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/86dbae23-1b54-48e1-bce2-28a6902aa67c/American+Journal+of+Geriatric+Psychiatry.png Functional Medicine Blog - The Triglyceride–Glucose Index is a powerful biomarker for cardiovascular disease, depression, dementia, cancer and much more - Association of Triglyceride-Glucose Index With Cognitive Function and Brain Atrophy: A Population-Based Study https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/4077265b-e206-4af4-b508-aeb949a30c3a/Translational+Oncology.png Functional Medicine Blog - The Triglyceride–Glucose Index is a powerful biomarker for cardiovascular disease, depression, dementia, cancer and much more - Breast Cancer Triglyceride-glucose index and triglyceride-glucose–body mass index as prognostic factors for early stage breast cancer patients receiving neoadjuvant chemotherapy https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/8a031e2e-350c-4a7e-b2ec-95900578b3be/Frontiers+in+Endocrinology.png Functional Medicine Blog - The Triglyceride–Glucose Index is a powerful biomarker for cardiovascular disease, depression, dementia, cancer and much more - Prostate Cancer Triglyceride-glucose index is a predictor of the risk of prostate cancer: a retrospective study based on a transprostatic aspiration biopsy population https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/693142cb-fe96-459a-a7c6-88cfe0aefd25/International+Journal+of+Clinical+Practice.png Functional Medicine Blog - The Triglyceride–Glucose Index is a powerful biomarker for cardiovascular disease, depression, dementia, cancer and much more - A novel prognostic risk factor for patients undergoing radical prostatectomy: Triglyceride-glucose index https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/0931ae14-9d33-4002-a6cf-0a21bc7bbec5/Cancer+Medicine.png Functional Medicine Blog - The Triglyceride–Glucose Index is a powerful biomarker for cardiovascular disease, depression, dementia, cancer and much more - Prediagnostic markers of insulin resistance and prostate cancer risk and death: A pooled study https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1b9a708c-681c-4881-8b73-c01cf0a2b30d/British+Journal+of+Cancer.png Functional Medicine Blog - The Triglyceride–Glucose Index is a powerful biomarker for cardiovascular disease, depression, dementia, cancer and much more - Body mass index, triglyceride-glucose index, and prostate cancer death: a mediation analysis in eight European cohorts https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/7e228edf-2609-4cf8-93b3-86b4583dedf4/Frontiers+in+Nutrition.png Functional Medicine Blog - The Triglyceride–Glucose Index is a powerful biomarker for cardiovascular disease, depression, dementia, cancer and much more - The mediating role of vitamin D in the relationship between triglyceride glucose index and mortality in patients with diabetes mellitus: a causal mediation analysis https://www.lapislight.com/lapislight/blog/atrial-fibrillation-coffee-cognition-ovnqt-c78pmb-bh756q-d9leb monthly 0.5 2025-02-25 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/41b3af36-663b-438b-b21a-7511d39f1f45/Journal+of+the+American+Heart+Association.png Functional Medicine Blog - Coffee improves cognition in people with atrial fibrillation Drinking up to or more than five cups of coffee per day helps prevent the cognitive decline associated with atrial fibrillation. https://www.lapislight.com/lapislight/blog/atrial-fibrillation-nt-probnp-n8egc-wp306k monthly 0.5 2025-01-20 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/12634530-cd09-46aa-bc92-f117853a23c0/heart.png Functional Medicine Blog - Atrial fibrillation risk identified early by NT-proBNP Recent research shows that NT-proBNP levels are strongly associated with an increased risk of afib (atrial fibrillation). https://www.lapislight.com/lapislight/blog/ketogenic-aging-senescence-ampk-e9nbq monthly 0.5 2024-12-23 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/2d89a998-e8f3-4bf4-b4b3-234d6fc94251/Science+Advances.png Functional Medicine Blog - Ketogenic diet can accelerate aging Research shows how the ketogenic diet can induce cellular senescence, increasing the number of aged and damaged cells. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/050f1b11-7579-4805-b380-687011fe7c8e/Ketogenic+diet+induces+SASP.png Functional Medicine Blog - Ketogenic diet can accelerate aging (B and C) TNFα, IL-1β, and IL-6 measured by ELISA in plasma collected from male (B) (n = 5, except 4 at baseline) and female (C) (n = 11) patients at baseline and after 3 and 6 months on a clinical KD trial. P values were calculated by one-way ANOVA followed by Dunnett’s multiple comparisons test. https://www.lapislight.com/lapislight/blog/ptsd-37kbi-cardio-4txuojn-8trauma-bg4865-ndd-ln38a-brain monthly 0.5 2023-12-27 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/4ccb3fab-acee-447a-a0f2-ae1ca9858a16/JAMA+Network+Open.png Functional Medicine Blog - Unresolved PTSD promotes adverse cardiovascular and brain effects PTSD symptoms are associated with more carotid atherosclerosis, brain small vessel disease and poorer cognitive performance. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/e71e5539-924c-4aae-9c71-827d8ede0ae2/JAMA+Network+Open+PTSD+CVD+Brain.png Functional Medicine Blog - Unresolved PTSD promotes adverse cardiovascular and brain effects - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/de03972a-e56d-436f-bf17-5e7e7aa53374/Associations+Between+Posttraumatic+Stress+Disorder+%28PTSD%29+Symptoms+and+White+Matter+Hyperintensity+Volume+%28WMHV%29.png Functional Medicine Blog - Unresolved PTSD promotes adverse cardiovascular and brain effects - Make it stand out Associations Between Posttraumatic Stress Disorder (PTSD) Symptoms and White Matter Hyperintensity Volume (WMHV) https://www.lapislight.com/lapislight/blog/stress-inflammation-brainspotting-37bsp-lap-9tu3azq-6pigbj-sk9750-vbra-nt8x monthly 0.5 2023-12-24 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/100c9102-200c-4afc-a1ca-27bd41b450e9/Nature+Reviews+Neuroscience.png Functional Medicine Blog - Stress-linked mental disorders, systemic inflammation, and Brainspotting Stress-linked disorders, including anxiety and depression, are associated with systemic inflammation. Brainspotting can calm the adverse somatic activation loop. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/2eb57d5e-7215-4953-9dd3-46b36d209a25/Breakdown+of+body+barriers+during+stress.png Functional Medicine Blog - Stress-linked mental disorders, systemic inflammation, and Brainspotting - Breakdown of body barriers during stress “Chronic stress or stress-relevant disorders, such as anxiety and depression, compromise the blood–brain barrier and gut epithelial barrier…inflammatory monocytes…and neutrophils…can enter the brain parenchyma through the damaged blood–brain barrier to directly influence neuronal excitability. In the intestine, stress increases IL-17 + T cell and mast cell accumulation…allowing lipopolysaccharide (LPS) to enter circulation from the gut lumen to activate pro-inflammatory signalling pathways. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/3a47125f-20ec-4a40-a56c-e0154de74b3a/Primal+World+Beliefs.png Functional Medicine Blog - Stress-linked mental disorders, systemic inflammation, and Brainspotting - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.lapislight.com/lapislight/blog/cholesterol-risk-misleading-53vnu-pek-2vl8dz-9cnuo-vf408-3n7d2 monthly 0.5 2023-06-10 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/363add9f-7035-42f0-8260-5fe760b71f93/Cureus+Journal+of+Medical+Science.png Functional Medicine Blog - Risks of high cholesterol and benefits of statins misrepresented by unacceptable scientific behavior Emphasizing relative risk over absolute risk greatly overestimates concerns about high cholesterol, a misleading trend in scientific reporting. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/e94889e2-151a-4a2c-b80e-d5557f468856/LRC-CPPT+data.png Functional Medicine Blog - Risks of high cholesterol and benefits of statins misrepresented by unacceptable scientific behavior - Comparison of absolute and relative risk benefits of cholesterol reduction in LRC-CPPT The actual 0.4 percentage point absolute risk difference in heart disease mortality is clinically meaningless. “How can the CHD mortality rate be reported as a 24% reduction in the publication, as well as in the medical journals that praised the findings, when the difference in CHD mortality between the two groups was only 0.4%? The explanation is that the AR mortality reduction of 0.4% was transformed into an RR reduction by dividing 0.4% by 2.0%, which resulted in a far more impressive 24% effect.” https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/c1aac384-3993-415e-8c61-2b85753a5986/MRFIT+Data.png Functional Medicine Blog - Risks of high cholesterol and benefits of statins misrepresented by unacceptable scientific behavior “A less alarming view of the MRFIT findings is provided by the overlapping AR data... The blue bars illustrate the AR of CHD in terms of the rate of survival in relation to cholesterol levels (the dashed line provides a visual guide at 99%, which indicates that at every level of cholesterol, the survival rate was approximately 99%). Thus, at the lowest level of cholesterol, CHD survival was 99.7%, and at the highest level of cholesterol, CHD survival was 98.7%. Thus, across the entire physiological range of cholesterol levels, the difference in the rate of six-year CHD mortality was only about one percentage point.” https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/cd75c8b3-08b7-4e0a-8003-c31b56f19ccf/JUPITER+data.png Functional Medicine Blog - Risks of high cholesterol and benefits of statins misrepresented by unacceptable scientific behavior - "This data in Table 3 of the original publication, which illustrates the great disparity between how the AR and RR represent the magnitude of rosuvastatin effects on coronary events. The dashed line at 99% is a visual aid to illustrate that over 99% of rosuvastatin (Crestor) and placebo subjects did not suffer from a fatal myocardial infarction (MI). If more than 99% of all subjects did not die as a result of an MI, how was it that the authors could claim that rosuvastatin reduced the rate of a fatal MI by 54%? The 0.41 percentage point absolute risk difference in MI mortality between the Crestor and placebo groups was converted into a 54% relative risk reduction in events.” https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/c74dc266-6b1b-4857-ada4-18e37d9156eb/Physician+decision+making+with+RR+and+AR+data.png Functional Medicine Blog - Risks of high cholesterol and benefits of statins misrepresented by unacceptable scientific behavior - Influence of data presented as relative risk versus absolute risk in patient and physician decision-making: “When the lipid-lowering effects were presented as RR, more than three-quarters of the clinicians were amenable to prescribing the medication, and even more of the patients were amenable to taking the medication. By contrast, when the data were presented as AR, only a quarter of the physicians were amenable to prescribing the medication, and less than half of the patients were amenable to taking the medication.” https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/78f66bfd-99e7-4bc7-8f5d-f16c1bd5beb4/JAMA+Internal+Medicine.png Functional Medicine Blog - Risks of high cholesterol and benefits of statins misrepresented by unacceptable scientific behavior If a biopsy is necessary, it’s time to demand a transperineal instead of a transrectal biopsy. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/63d67e46-446e-4957-84fc-fd0dc1ce5c95/JAMA+Internal+Medicine+Paper.png Functional Medicine Blog - Risks of high cholesterol and benefits of statins misrepresented by unacceptable scientific behavior Another study published last year in JAMA (Journal of the American Medical Association) Internal Medicine also examined the same problem of misrepresenting data with regard to cholesterol and statins in a systematic review and meta-analysis, Evaluating the Association Between Low-Density Lipoprotein Cholesterol Reduction and Relative and Absolute Effects of Statin Treatment, and came to the same conclusions. https://www.lapislight.com/lapislight/blog/phototherapy-light-dementia-28chw-spb-7vr8lq-2pjvq-ve936-coqzs monthly 0.5 2023-10-08 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/64cbc6df-491b-4c49-ae21-a89dfe13c9de/Brain+and+Behavior.png Functional Medicine Blog - Phototherapy and photobiomodulation can improve cognitive function in dementia Decline in cognitive function in dementia improved significantly with phototherapy (light therapy). https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/3cf0a231-ffe8-4703-adbb-f0c95cc0852c/MIT+School+of+Science.png Functional Medicine Blog - Phototherapy and photobiomodulation can improve cognitive function in dementia Keeping Aging Brains Healthy https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/e0f5ebb6-e896-4fe7-953f-7f3c8bcf928e/mouse+brain.png Functional Medicine Blog - Phototherapy and photobiomodulation can improve cognitive function in dementia “With 40-hertz light therapy, Alzheimer’s patients may one day be able to treat themselves—perhaps wearing a special headset that emits the flickering light. Here, we see a slice of a mouse brain exposed to light therapy causing a reversal of severe neurodegeneration.” https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/614a14b9-4572-466b-953d-8567a465329c/Auragen.png Functional Medicine Blog - Phototherapy and photobiomodulation can improve cognitive function in dementia Cognitive Optimization with Gamma Light and Sound Therapy - Auragen 40Hz Synchronized Gamma Optimal Visual and Auditory Delivery https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/5c252b82-d56f-424c-b39d-60759fa48192/Neuronic.png Functional Medicine Blog - Phototherapy and photobiomodulation can improve cognitive function in dementia The Neuronic Neuradiant 1070 for transcranial photobiomodulation therapy. https://www.lapislight.com/lapislight/blog/atrial-fibulation-afib-59obn-bpw-3cs9bn-9kafib-hj352-bbrp-qa7d4 monthly 0.5 2025-01-27 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/5ce9ae8e-20ad-4297-a9fc-7edc1006bc12/Circulation+Journal.png Functional Medicine Blog - Atrial fibrillation caused by autoimmunity There is a wealth of evidence for the role of autoimmune inflammation causing or contributing to afib (atrial fibrillation) that should be attended to in case management. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/42c291a4-748a-41db-be53-b785f2d0740a/EP+Europace.png Functional Medicine Blog - Atrial fibrillation caused by autoimmunity Autoimmune diseases and new-onset atrial fibrillation: a UK Biobank study: “(Systemic) inflammation is suggested to be associated with atrial fibrillation development. Autoimmune diseases can be used to assess underlying (sub)clinical inflammation.” https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/a2470376-28f9-4075-b13b-f1a08c0596dc/Medicine.png Functional Medicine Blog - Atrial fibrillation caused by autoimmunity - Autoimmune activation as a determinant of atrial fibrillation among Turks “Current main findings of “paradoxical” lower total and LDL-cholesterol levels…strongly support the hypothesis that autoimmune activation is the mechanism underlying the development of persistent AF.” https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/49a64703-7a0f-416c-9a7f-66ecf8169264/Nature+Reviews+Cardiology.png Functional Medicine Blog - Atrial fibrillation caused by autoimmunity - Inflammation and the pathogenesis of atrial fibrillation Inflammation and its associated immune response are involved in the initiation and maintenance of atrial fibrillation (AF) https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/d7a3aa60-3228-44cd-8a7e-5dd5898b324b/Angiology.png Functional Medicine Blog - Atrial fibrillation caused by autoimmunity - Clinical Aspects of Systemic Inflammation and Arrhythmogenesis, Especially Atrial Fibrillation “…any disease with increased association with inflammation could be a trigger for increased CV risk including arrhythmias, especially highly prevalent AF.” https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/8578b493-f1d4-45c7-8374-e74f6d08ac0f/Current+Cardiology+Reports.png Functional Medicine Blog - Atrial fibrillation caused by autoimmunity - The Role of Autoantibodies in Arrhythmogenesis “The time has come to acknowledge autoimmune cardiac arrhythmias as a distinct disease entity. Establishing the autoantibody profile of patients will help to develop novel treatment approaches for patients.” https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/60354664-31ea-48e3-874d-bf3751c744df/Heart+Rhythm.png Functional Medicine Blog - Atrial fibrillation caused by autoimmunity - Autoantibodies and Cardiac Arrhythmias “Recent studies indicate that autoantibodies play an important role in the development of cardiac arrhythmias, including atrial fibrillation, modulation of autonomic influences on heart rate and rhythm, conduction system abnormalities, and ventricular arrhythmias…there is substantial evidence that autoantibodies play an important role in the development of cardiac arrhythmias in a wide range of disease conditions.” https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/5d802c97-0bba-4d10-aba4-4c5c83c10e09/Autoantibodies+and+cardiac+arrhythmias.+.jpg Functional Medicine Blog - Atrial fibrillation caused by autoimmunity - Make it stand out Autoantibodies and cardiac arrhythmias. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/3345f92a-57d3-44c3-b158-5d563b1d96da/International+Journal+of+Molecular+Sciences.png Functional Medicine Blog - Atrial fibrillation caused by autoimmunity - Autoantibodies in Atrial Fibrillation—State of the Art “There is increasing evidence suggesting that autoimmunity is an important factor in the initiation and perpetuation of AF.” https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/62b9a656-4911-4df3-a3c6-8213ea32836c/Pathomechanisms+of+AF+initiation+and+maintenance+with+the+possible+role+of+autoantibodies.jpg Functional Medicine Blog - Atrial fibrillation caused by autoimmunity - Make it stand out Pathomechanisms of AF initiation and maintenance with the possible role of autoantibodies. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/885ab2c2-1d7c-4470-9cf1-0069e8e8e351/Graphical+summary+of+the+role+of+different+autoantibodies+in+atrial+fibrillation+with+a+probable+pathomechanism+of+action+if+known..png Functional Medicine Blog - Atrial fibrillation caused by autoimmunity Graphical summary of the role of different autoantibodies in atrial fibrillation with a probable pathomechanism of action if known. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/c585ad60-e130-4e10-8ce8-e3d9e87e7bfe/Reviews+on+Recent+Clinical+Trials.png Functional Medicine Blog - Atrial fibrillation caused by autoimmunity - Atrial Fibrillation in Autoimmune Rheumatic Diseases: from Pathogenesis to Treatment “(AF)…onset and maintenance requires the presence of an arrhythmogenic substrate that predisposes the patient for risk of these types of arrhythmias and the occurrence of a trigger event.” https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/ff0e635d-9a36-4afa-818f-cc3f27f6ef1a/Atrial+Fibrillation+in+Autoimmune+Rheumatic+Diseases.png Functional Medicine Blog - Atrial fibrillation caused by autoimmunity - Make it stand out Atrial Fibrillation in Autoimmune Rheumatic Diseases https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/613a9844-ddc3-4b4a-8346-7e81fcf8ad04/Indian+Journal+of+Dermatology%2C+Venereology+%26+Leprology.png Functional Medicine Blog - Atrial fibrillation caused by autoimmunity - Increased risk of atrial fibrillation in patients with psoriasis: A meta-analysis of observational studies “Our results showed that psoriasis is significantly associated with an increased risk of developing atrial fibrillation.” https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/6c0887bf-c4a8-45fe-b733-6559772636ab/Journal+of+the+American+Heart+Association.png Functional Medicine Blog - Atrial fibrillation caused by autoimmunity - Association of Autoimmune Vasculitis and Incident Atrial Fibrillation: A Population‐Based Case‐Control Study “Autoimmune vasculitis is significantly associated with AF and independently confers worse survival. These observations may represent one mechanism linking autoimmunity and inflammation to the pathogenesis and prognosis of AF.” https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/3d26487d-0e42-4c37-8bb3-c20f0fddf940/Cureus+Journal+of+Medical+Science.png Functional Medicine Blog - Atrial fibrillation caused by autoimmunity - Celiac Disease and Risk of Atrial Fibrillation: A Meta-analysis and Systematic Review “A significant association between celiac disease and risk of atrial fibrillation was reported in this study.” https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/36f118e4-a0b1-447a-9684-368a8577de55/European+Heart+Journal.png Functional Medicine Blog - Atrial fibrillation caused by autoimmunity - Increased risk of atrial fibrillation in patients with coeliac disease: a nationwide cohort study “Our results indicate that patients with coeliac disease, verified by intestinal biopsy, are at increased risk of atrial fibrillation… Adjustment for hypertension did not alter the HR for AF and hypertension therefore seems unlikely to explain the increased risk of AF in CD.” https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/06b8a4c9-2a09-442c-8173-ee41b6632080/Biomolecules.png Functional Medicine Blog - Atrial fibrillation caused by autoimmunity - Make it stand out Potential Impact of Oral Inflammations on Cardiac Functions and Atrial Fibrillation https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1ab8967b-e0cb-4723-bf54-63c564638ab6/Potential+role+of+the+oral+inflammation+in+the+pathogenesis+of+atrial+fibrillation..png Functional Medicine Blog - Atrial fibrillation caused by autoimmunity Potential role of the oral inflammation in the pathogenesis of atrial fibrillation. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/96d17267-38e7-4111-9538-f66783df8700/Potential+role+of+the+autonomous+nervous+system+in+the+pathophysiology+of+atrial+fibrillation..png Functional Medicine Blog - Atrial fibrillation caused by autoimmunity - Make it stand out Potential role of the autonomous nervous system in the pathophysiology of atrial fibrillation. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/267a2a03-6947-4e28-b00d-66d127e0e642/Current+Opinion+in+Cardiology.png Functional Medicine Blog - Atrial fibrillation caused by autoimmunity - The functional medicine approach to atrial fibrillation: can a cure for atrial fibrillation be found in the gut? https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/60354664-31ea-48e3-874d-bf3751c744df/Heart+Rhythm.png Functional Medicine Blog - Atrial fibrillation caused by autoimmunity - Inappropriate sinus tachycardia may be related to an immunologic disorder involving cardiac beta andrenergic receptors https://www.lapislight.com/lapislight/blog/red-blood-cells-immune-activity-inflammation-jeic monthly 0.5 2023-04-26 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/c4bd9782-458b-455a-9ac7-bb9a4e39d255/Science+Translational+Medicine.jpg Functional Medicine Blog - Red blood cells’ previously unknown immune activity in anemia of inflammation Red blood cells function as immune sensors during infection and help drive inflammation resulting in anemia. https://www.lapislight.com/lapislight/blog/cpap-mask-nasal-94mas-xbq-3vl8wp-6ovhs-bq9cn monthly 0.5 2023-04-21 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/70b77635-06aa-4f68-a6b6-17104d38c90f/Chest.png Functional Medicine Blog - CPAP oronasal masks collapse the airway more than nasal masks Oronasal masks have an adverse effect on airway anatomy and function compared to nasal masks. https://www.lapislight.com/lapislight/blog/contraceptive-hormones-reduce-78vnw-wpa-2bg8qa-3pgqo-037vh monthly 0.5 2023-04-18 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/ad886ba1-3e98-4d0c-b90b-d3534df65469/PLOS+Computational+Biology.png Functional Medicine Blog - Oral contraceptive hormone doses could be reduced by over 90% Almost no prenatal dietary supplements provide key nutrients in the doses needed for pregnant women… https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/3df57fea-62ce-4f42-8a18-07d3ad88f644/Normal+menstrual+cycle+1.png Functional Medicine Blog - Oral contraceptive hormone doses could be reduced by over 90% - Make it stand out The figure shows the transition of a follicle, from its growth in the follicular phase to its rupture during ovulation, as well as its transformation to a corpus luteum and degradation in the luteal phase. The blue arrow indicates the control of the hypothalamus in the secretion of pituitary hormones. The black arrows represent the influence of the pituitary system on the ovarian system through FSH and LH, and the orange arrows show the response of the ovarian system through E2, P4, and Inh. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/c0d8e506-9ffa-4ed8-a28f-76b1fbfa63a7/Normal+menstrual+cycle+2.png Functional Medicine Blog - Oral contraceptive hormone doses could be reduced by over 90% - Make it stand out Pituitary and ovarian hormone levels in a normal menstrual cycle. The hormones LH, FSH, and E2 peak in the late follicular phase while P4 and Inh reach maximum value in the luteal phase. https://www.lapislight.com/lapislight/blog/prostate-cancer-encouraging-89pro-sca-1eg3ot-7kegp-xw670 monthly 0.5 2023-04-16 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1640740941299-WF2GU16Y1TUD2OM7XTEB/New+England+Journal+of+Medicine.png Functional Medicine Blog - Encouraging news for prostate cancer and a better way to biopsy After 15 years, prostate cancer–specific mortality was low regardless of the treatment assigned… https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/5702ecdd-ce82-4566-aa20-7f9822a74077/EAU23-logo-website.png Functional Medicine Blog - Encouraging news for prostate cancer and a better way to biopsy If a biopsy is necessary, it’s time to demand a transperineal instead of a transrectal biopsy. https://www.lapislight.com/lapislight/blog/prenatal-supplements-lacking-36rdw-fip-8dx2ps-5cspk monthly 0.5 2023-04-08 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/c53fb5ad-c873-41f7-a5e2-847ce6e8ecc2/The+American+Journal+of+Clinical+Nutrition.png Functional Medicine Blog - Most prenatal supplements do not provide enough key nutrients Almost no prenatal dietary supplements provide key nutrients in the doses needed for pregnant women… https://www.lapislight.com/lapislight/blog/calcium-vitamin-d-bone-11dens-bone-c1115-bmd8p monthly 0.5 2023-03-21 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1618872538306-VVY9O6F94DVLKXQDICQF/Cochrane-Library-300x74.png Functional Medicine Blog - Calcium and vitamin D supplements do not increase bone density in premenopausal women A Cochrane Review showed no improvement in bone mineral density. https://www.lapislight.com/lapislight/blog/vagus-stimulation-stomach-44tld-nje-5hu8cd-w8htf-w787j monthly 0.5 2023-02-22 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/4a0ca14d-3cd2-4298-926f-b4dead208778/Brain+Stimulation.png Functional Medicine Blog - How vagus nerve stimulation improves stomach function Transcutaneous auricular vagus nerve stimulation boosts stomach-brain communication and the regulation of digestion via via an NTS-midbrain pathway. https://www.lapislight.com/lapislight/blog/telomere-oxidative-senescence-12oxo-gua-8ni6se-f3ith monthly 0.5 2022-12-18 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/3607ddd0-900d-40f0-880b-fedc5680d33f/Nature+Structural+%26+Molecular+Biology.png Functional Medicine Blog - Telomere dysfunction without shortening also drives immunosenescence Oxidative damage can rapidly cause telomeres to no longer function, resulting in the ‘zombie cells’ characteristic of immunosenescence—in the absence of shortening. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/6cb9cb75-32f6-4cfc-9e32-1668e1881cbf/Model+for+telomere+8oxoG+induced+senescence.png Functional Medicine Blog - Telomere dysfunction without shortening also drives immunosenescence - Make it stand out Model for telomere 8oxoG induced senescence https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/b13d4ad0-8be6-4f6c-bf28-b5664ebe3eb6/Diseases+associated+with+oxidative+stress%2C+chronic+inflammation+and+shortened+telomeres.png Functional Medicine Blog - Telomere dysfunction without shortening also drives immunosenescence - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.lapislight.com/lapislight/blog/nordic-walking-cardiovascular-72nor-wal-6tt3ld-igyrh monthly 0.5 2022-07-23 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/0c79e6ce-b75c-4a7e-8a77-a553adb35c28/Canadian+Journal+of+Cardiology.png Functional Medicine Blog - Nordic walking beats HIIT exercise for cardiovascular benefits Nordic walking surpassed HIIT and MICT exercise in improving functional capacity in subjects with coronary artery disease. https://www.lapislight.com/lapislight/blog/vaccination-reaction-83vacc-rxn-6lgb8ptd-rd42t monthly 0.5 2022-07-09 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/553b28aa-bb49-4e92-9676-584a174b94b4/Vaccines.png Functional Medicine Blog - Skip the hot bath after your COVID shot New research reviews the various adverse effects that can occur following COVID-19 vaccination and highlights several activities to avoid that can exacerbate the reactions. https://www.lapislight.com/lapislight/blog/calcium-supplementation-heart-attack-risk-48hrm-str-2hs8ld monthly 0.5 2022-07-19 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/3a6e77cc-7118-471e-ad7b-a6576d289ee1/Nutrients.png Functional Medicine Blog - Calcium supplementation increases heart attack risk in large study In this enormous real-world study, heart attacks, strokes, and mortality in general were significantly increased by calcium supplementation. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/615e6cd5-3aa3-4481-9fc2-e54c4e1c5c00/Open+Heart.png Functional Medicine Blog - Calcium supplementation increases heart attack risk in large study - Subclinical magnesium deficiency: a principal driver of cardiovascular disease and a public health crisis, published in Open Heart, an official journal of the British Cardiovascular Society and the BMJ, describes the scope and significance of suboptimal levels of magnesium for cardiovascular health. “‘Hypomagnesemia is a relatively common occurrence in clinical medicine. That it often goes unrecognized is due to the fact that magnesium levels are rarely evaluated since few clinicians are aware of the many clinical states in which deficiency, or excess, of this ion may occur’.28” https://www.lapislight.com/lapislight/blog/immunosenescnece-stress-78imm-sen-4ab1zd monthly 0.5 2022-07-03 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/810daecb-3fa9-413f-bcdd-84c55c161ada/PNAS.png Functional Medicine Blog - Immunosenescence—immune deterioration associated with age—and social stress Immunosenescence, immune system exhaustion associated with aging, can be accelerated by additional factors including stress. https://www.lapislight.com/lapislight/blog/prediabetes-heart-attacks-linked-349hit-insu-7cdig8 monthly 0.5 2023-04-07 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/e720d4c1-0d69-4766-843a-9a9f9b908f7f/Endocrine+Society+Conference+2022.png Functional Medicine Blog - Prediabetes is linked to heart attacks - Endocrine Society Conference 2022 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/31978f01-dfbf-4c5e-a2cc-250c2c503d97/Circulation+Research.png Functional Medicine Blog - Prediabetes is linked to heart attacks - In The Vasculature in Prediabetes published in Circulation Research in 2018, point out the leading roles played by insulin and inflammation in damaging the the endothelium (the living inner wall of blood vessels). “In prediabetes, hyperglycemia, insulin resistance, and inflammation and metabolic derangements associated with concomitant obesity cause endothelial vasodilator and fibrinolytic dysfunction, leading to increased risk of cardiovascular and renal disease.” https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/11791bc5-b165-4d3f-b060-6fb8dd8f5504/1135fig01.png Functional Medicine Blog - Prediabetes is linked to heart attacks - Make it stand out Endothelial insulin resistance, hyperglycemia and the formation of advanced glycation products, and increased free fatty acids (FFAs) give rise to oxidative stress, inflammation and endothelial vasodilator, and fibrinolytic dysfunction in prediabetes. PAI-1 indicates plasminogen activator inhibitor-1; RAAS renin–angiotensin–aldosterone system; and VAT, visceral adipose tissue. https://www.lapislight.com/lapislight/blog/menopause-medical-experience-47ute-mona-k2794 monthly 0.5 2023-03-19 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/e5ae4543-eaa8-4f15-96f7-2b2c329743c1/BMJ+Open.png Functional Medicine Blog - Enriching the conversation about menopause Two OBGYNs with two health psychologists just penned a thought-provoking article. https://www.lapislight.com/lapislight/blog/mothers-hrv-calms-distressed-babies-39mot-bab-4mb5cm monthly 0.5 2022-06-23 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/d2fbf2ae-eb2c-42a0-9648-e138ebedaf37/Journal+of+Psychopathology+and+Clinical+Science.png Functional Medicine Blog - Overcoming postpartum depression to calm distressed babies with heart rate variability Mother’s heart rate can calm a baby when her heart rate variability pattern expresses a state of ease to which the baby then naturally synchronizes. https://www.lapislight.com/lapislight/blog/pain-prolonged-by-medications-79tus-opru monthly 0.5 2022-06-19 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/9b2af1fa-d38d-4c0f-966c-8cf4adaf59cf/Science+Translational+Medicine.png Functional Medicine Blog - Pain is often prolonged by anti-inflammatory drugs Medications such as NSAIDs (non-steroidal anti-inflammatory drugs) and steroids, while offering immediate temporary pain relief, can promote the transition from a an acute to a chronic pain state. https://www.lapislight.com/lapislight/blog/long-covid-pasc-factors-keid-98nug monthly 0.5 2022-05-22 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/984b270e-7496-412b-a8a7-6f4a087f3a36/Cell.png Functional Medicine Blog - Four factors shown to predict long COVID Post-acute sequelae of COVID-19 (PASC), aka ‘long COVID’, is an emerging health care crisis. Clinical factors have been identified that predict the risk of progression to PASC. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/6c601ca6-4e6c-4cf9-bde9-a7630530f116/Factors+predicting+PASC.png Functional Medicine Blog - Four factors shown to predict long COVID - Make it stand out Antidepressant effect of transcutaneous auricular vagus nerve stimulation. https://www.lapislight.com/lapislight/blog/tvns-relieves-depression-neuroinflammation-jfgu monthly 0.5 2022-01-27 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/508890b6-4677-463b-8c51-4d1381cc3f1c/Journal+of+Neuroinflammation.png Functional Medicine Blog - Transcutaneous vagus nerve stimulation relieves depression by reducing brain inflammation There is a large body of scientific evidence validating the effectiveness of transcutaneous vagus nerve stimulation (tVNS) in the treatment of depression. tVNS is inexpensive and easy to do at home. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/cbb6043c-dc63-4fc0-abd1-d5eca32c19a1/Antidepressant+effect+of+taVNS.png Functional Medicine Blog - Transcutaneous vagus nerve stimulation relieves depression by reducing brain inflammation - Make it stand out Antidepressant effect of transcutaneous auricular vagus nerve stimulation. https://www.lapislight.com/lapislight/blog/fasting-mimicking-diet-benefits-for-cancer-patients monthly 0.5 2022-01-01 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1f68548b-8657-488c-9f57-2e696652fdab/Cancer+Discovery.png Functional Medicine Blog - Fasting-mimicking diet benefits for cancer patients Fasting-mimicking diet is safe and reshapes metabolism and antitumor immunity in cancer patients https://www.lapislight.com/lapislight/blog/anti-idiotype-antibodies-sars-cov-2-spike-protein-ghid monthly 0.5 2021-12-29 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/9f566643-dd8c-4a67-b435-92d4def12ff0/New+England+Journal+of+Medicine.png Functional Medicine Blog - Anti-idiotype antibodies and symptoms after SARS-CoV-2 infection or vaccination - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/06cff94c-c601-4d87-9df8-83648ea58f3f/Anti-idiotype+Antibodies+and+SARS-CoV-2.png Functional Medicine Blog - Anti-idiotype antibodies and symptoms after SARS-CoV-2 infection or vaccination - Make it stand out Anti-idiotype Antibodies and SARS-CoV-2 https://www.lapislight.com/lapislight/blog/what-level-of-neutralizing-antibodies-protects-against-covid monthly 0.5 2021-12-30 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1633298609088-1QJ4HTEWZ59CF1XMHHRG/Journal+of+Infection.png Functional Medicine Blog - What level of neutralizing antibodies protects against COVID? - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1633299704389-RZMRN1E7PQ2IF3OTM92Q/Protection+against+SARS-CoV-2+according+to+neutralizing+%28A%29+or+binding+%28B%29+antibody+classes. Functional Medicine Blog - What level of neutralizing antibodies protects against COVID? - Make it stand out Protection against SARS-CoV-2 according to neutralizing (A) or binding (B) antibody classes. https://www.lapislight.com/lapislight/blog/covids-comet-tail-of-autoimmunity monthly 0.5 2021-12-30 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1629069516463-2Q2HVKFJ3KV7TNWJM6ZD/World+Journal+of+Clinical+Cases.png Functional Medicine Blog - COVID’s ‘comet tail’ of autoimmunity - SARS-CoV-2, like many other infections, can trigger latent or instigate new autoimmunity. It is exceptional compared to many other pathogens in… https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1631487780530-KBPVAMG50KXKI2FCPK0X/Immunologic+pathways+activated+by+severe+acute+respiratory+syndrome+coronavirus+2.png Functional Medicine Blog - COVID’s ‘comet tail’ of autoimmunity - Make it stand out Immunologic pathways activated by severe acute respiratory syndrome coronavirus 2 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1631488032068-8MOCMHZRYZS0WBTGX1YA/Localization+of+autoimmune+responses+triggered+by+COVID-19.png Functional Medicine Blog - COVID’s ‘comet tail’ of autoimmunity - Make it stand out Localization of autoimmune responses triggered by COVID-19 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1631491195532-6TWHJUJZCVKOBU21KHOX/Nature+Vol.+595+No.+7866.png Functional Medicine Blog - COVID’s ‘comet tail’ of autoimmunity - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1631994570174-UG3F8R329W4ODL85TGZS/Nature+Outlook+Autoimmune+Disease.png Functional Medicine Blog - COVID’s ‘comet tail’ of autoimmunity - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1631993921708-MHXE7U9AUN4VWMDAICMB/ACS+Chemical+Neuroscience.png Functional Medicine Blog - COVID’s ‘comet tail’ of autoimmunity - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1632004995144-O227G2T1T9A7T5SJS5FR/CNS+self-tissue+damage.png Functional Medicine Blog - COVID’s ‘comet tail’ of autoimmunity - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1632006260164-TDHYQPO5OVZ7EHONY7WM/Mechanisms+of+virus-activated+CNS+autoimmunity.png Functional Medicine Blog - COVID’s ‘comet tail’ of autoimmunity - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1632007136828-8XA8KCCMV65WWPDMB316/Nature+Communications.png Functional Medicine Blog - COVID’s ‘comet tail’ of autoimmunity - And just the other day a paper published in Nature Communications documents the presence of new-onset IgG autoantibodies in hospitalized patients with COVID-19. https://www.lapislight.com/lapislight/blog/insulin-levels-change-before-changes-in-weight-and-obesity monthly 0.5 2021-12-30 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1624997967393-TL2YA2F2IFJ9U9XJXI5A/JAMA+Network+Open.png Functional Medicine Blog - Insulin levels change before weight loss or obesity - High insulin levels, provoked by spikes in blood glucose due to high glycemic foods or stress chemistry, block the metabolism of calories for energy and force them to be stored as visceral fat. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1625081948787-2BSTTJC122F0Z5J19YZZ/Journal+of+Hepatology.png Functional Medicine Blog - Insulin levels change before weight loss or obesity - An example of how insulin drives fat production is offered by a study recently published in the Journal of Hepatology demonstrating that fructose and sucrose increase hepatic lipogenesis (fat production in the liver) and promote long-term metabolic dysfunction. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1625189303223-G72KSQ96P3A962NIWS1C/Fat+production+from+fructose+and+sucrose.png Functional Medicine Blog - Insulin levels change before weight loss or obesity - Regular consumption of both fructose- and sucrose-sweetened beverages in moderate doses – even when associated with stable caloric intake - https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1625250417230-VUEQ0XTCAZ6MW4T7F6FM/2021-07-02_11-25-20.png Functional Medicine Blog - Insulin levels change before weight loss or obesity - In an interview by Technology Networks Proteomics and Metabolomics, the authors state: “Eighty grams of sugar daily, which is equivalent to about 0,8 liters of a normal soft drink, boosts fat production in the liver…” https://www.lapislight.com/lapislight/blog/non-specific-symptoms-occurs-years-before-multiple-sclerosis-diagnosis monthly 0.5 2021-12-30 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1624643201772-N3X3TT3T3LODOXFABWG3/Neurology.png Functional Medicine Blog - Non-specific symptoms occur years before multiple sclerosis diagnosis - A paper just published in the journal Neurology documents that diffuse, non-specific symptoms are experienced years before the diagnostic criteria for multiple sclerosis (MS) are satisfied. This illustrates the ‘prodrome’ that is typical of a wide variety of autoimmune disorders. It highlights the importance of investigating antibodies to self-tissue (autoantibodies) classified as ‘predictive’ when they occur before any symptoms and ‘reactive’ when there are symptoms present but the condition has not yet advanced to the pathological stage that qualifies for the canonical diagnosis of an autoimmune disease. https://www.lapislight.com/lapislight/blog/hepatic-stellate-cell-suppression-of-natural-killer-cells monthly 0.5 2021-12-30 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1624128376440-VOYDQ8FSOE2XWG6X9SPD/Nature+3+June+2021.png Functional Medicine Blog - Hepatic stellate cells suppress natural killer cells allowing cancers cells to ‘wake up’ - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1624133149472-04Z19X6RHSYJC4VX6MPX/Interactions+that+affect+the+dormancy+of+tumour+cells.png Functional Medicine Blog - Hepatic stellate cells suppress natural killer cells allowing cancers cells to ‘wake up’ - “…depleting NK cells…led to higher levels of metastases in the liver. However, if NK cells were boosted using the cytokine IL-15, this prevented the formation of liver metastases and tumour cells remained dormant…the size of the pool of NK cells in the liver environment determines whether dormancy occurs or metastases form.” https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1624144649542-P6L6Y6M0PUT0BXIM8LO7/Impact+of+HSCs+on+NK+cell+anti-fibrotic+functions+in+LC+patients+with+HBV+infection.png Functional Medicine Blog - Hepatic stellate cells suppress natural killer cells allowing cancers cells to ‘wake up’ - “These data suggested that fully activated α-SMA+ HSCs produce a large amount of TGF-β that subsequently deactivates NK cells and inhibits their anti-fibrotic effect, particularly in advanced LC patients…Taken together, these findings suggested that HSCs have a great impact on hepatic NK cell anti-fibrotic functions via TGF-β, which suppresses NK cells’ killing capacity and IFN-γ production, and induces NK apoptosis…” https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1624146015584-HLD6SYGX5514T5KACFBB/World+Journal+of+Gastroenterology.png Functional Medicine Blog - Hepatic stellate cells suppress natural killer cells allowing cancers cells to ‘wake up’ - “…the natural polyphenol flavonoid resveratrol has a broad range of beneficial biological functions…” https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1624209755045-30OHPUZARQAN8HW9LVRO/MSK+Cancer+Center.png Functional Medicine Blog - Hepatic stellate cells suppress natural killer cells allowing cancers cells to ‘wake up’ - NK cells need fuel to engage in the work of making cancer cells dormant. How they are fueled is described a study conducted at Memorial Sloan Kettering recently published in Cell Reports that reveals the central role of glycolysis in NK metabolism. https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1624152589092-WOW7LA96VIAV8Q2XCCTU/NK+cells+aerobic+glycolysis+and+LDHA.png Functional Medicine Blog - Hepatic stellate cells suppress natural killer cells allowing cancers cells to ‘wake up’ - “Natural killer (NK) cells are…capable of rapid cytotoxicity, cytokine secretion, and clonal expansion. To sustain such energetically demanding processes, NK cells must increase their metabolic capacity upon activation. …we investigated the role of aerobic glycolysis in NK cell function and demonstrate that their glycolytic rate increases rapidly following viral infection and inflammation, prior to that of CD8+ T cells.” https://www.lapislight.com/lapislight/blog/2021/01/21/maternal-autoimmunity-associated-adhd monthly 0.5 2021-12-30 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1618871864755-WB6DKDUGAPDHZSXQUNL1/JAMA-Pediatrics.png Functional Medicine Blog - Maternal autoimmunity associated with ADHD in children JAMA Pediatrics: Association of Maternal Autoimmune Disease With Attention-Deficit/Hyperactivity Disorder in Children https://www.lapislight.com/lapislight/blog/2020/10/02/probiotics-use-caution-with-autoimmune-disease monthly 0.5 2021-04-20 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1618871863969-OSZVPK48H3P1UCQBBASR/Advances-in-Immunology.png Functional Medicine Blog - Probiotics: use caution with autoimmune disease https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1618871864564-2SLKT2LUQR0KDJQ1N7A2/Local-versus-peripheral-effects-of-Lactobacillus-spp.png Functional Medicine Blog - Probiotics: use caution with autoimmune disease Different probiotics may exert local and distant pro-inflammatory or protective effects depending on the host background and environment. https://www.lapislight.com/lapislight/blog/2020/04/23/autoimmunity-infection-induced monthly 0.5 2021-04-19 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1618871851072-6DSGKT1V2DFQ9Y46LZ41/Arthritis-Rheumatology.png Functional Medicine Blog - Induction of autoimmunity by infection Increasing Prevalence of Antinuclear Antibodies in the United States https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1618871863100-3L1KSONRPSIG79G0U4TL/The-Journal-of-Clinical-Investigation.png Functional Medicine Blog - Induction of autoimmunity by infection https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1618871853770-MSOWQHQ3SJW616GLHO66/Clinical-Experimental-Immunology.png Functional Medicine Blog - Induction of autoimmunity by infection https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1618871855936-2RM4WX79844FBEQX7TWK/Impact-of-pathogens-on-autoimmunity-2.png Functional Medicine Blog - Induction of autoimmunity by infection Pathogens in Autoimmune Disease https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1618871854965-71C0C4GPJIVC285N0SCX/Clinical-Microbiology-Reviews.png Functional Medicine Blog - Induction of autoimmunity by infection Molecular Mimicry, Bystander Activation, or Viral Persistence: Infections and Autoimmune Disease https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1618871858117-9EK8O5XWC39SI23YOSDU/Journal-of-Autoimmunity.png Functional Medicine Blog - Induction of autoimmunity by infection https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1618871855753-50M683L4812DHG1YY2I1/Immunologic-Research.png Functional Medicine Blog - Induction of autoimmunity by infection Revisiting the old link between infection and autoimmune disease with commensals and T helper 17 cells https://www.lapislight.com/lapislight/blog/2020/04/19/covid-19-immune-mental-health monthly 0.5 2021-06-01 https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1618871860189-9YZ90XY53QESB49KCNAF/Medscape-Psychiatry.png Functional Medicine Blog - COVID-19 and immune effects on mental health https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1618871857711-D8MYT8J6RIWE8J0ZW1JW/JAMA-Internal-Medicine-1.png Functional Medicine Blog - COVID-19 and immune effects on mental health https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1618871851573-9KR5B8CGIOXJU0R4H0YB/Brain-Behavior-and-Immunity.png Functional Medicine Blog - COVID-19 and immune effects on mental health Are we facing a crashing wave of neuropsychiatric sequelae of COVID-19? Neuropsychiatric symptoms and potential immunologic mechanisms https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1618871855193-IJXP7STKBSATHXHO4POS/Depression-and-Anxiety.png Functional Medicine Blog - COVID-19 and immune effects on mental health The association between inflammatory dysregulation and diagnoses associated with chronic, impactful, and severe anxiety https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1618871850671-8AD2D11T5SP0B3A10D8R/Anxiety-and-Depression-Conference.png Functional Medicine Blog - COVID-19 and immune effects on mental health https://images.squarespace-cdn.com/content/v1/6078e2ab7ca55d3b1db62953/1618871858768-4KWEWV7NVJEA0IFWYVUP/Journal-of-Evaluation-in-Clinical-Practice.png Functional Medicine Blog - COVID-19 and immune effects on mental health https://www.lapislight.com/lapislight/blog/2020/04/13/balancing-immunity-inflammation-lung-disease monthly 0.5 2021-06-01 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